Pause sub
psychiatric illnesses for a long
time had been just looked at
under the domain of behavioral
symptoms but near progress we're
starting to see that it's not
just about symptoms and behavior
it's looking at the whole
picture I'm both her
psychiatrist and an
anthropologist and professor of
cell biology physiology and
neuroscience and psychology I am
a general internist I'm a
medical anthropologist professor
of radiology
I'm spectroscopy my name is
Dolores Malaspina and I found it
and direct the inspires program
the Institute for Social in
psychiatric initiative here at
NYU Bellevue inspires is a
multidisciplinary team and our
conversations really cut across
scientific disciplines to try to
better arrive at an
understanding of severe mental
illness and the metabolic
diseases that are so closely
associated with mental illness
my area focuses in obesity and
I've been collaborating with
Dolores now is being on a bunch
of projects and one of the
projects was around looking at
this more closely in psychiatry
what are psychiatrists doing
with regards to weed management
counseling because we know that
a lot of the treatment for
obesity can also help with
mental health and a lot of the
causes of obesity have to do
with someone's mental health
status and so we looked at a
dataset looking at their
counseling of patients around
weight management issues and
found a lake in primary care and
there's a lot of areas for
have been collaborating with
inspire snow nine years to apply
imaging metrics both what's
called for dry fields 7332
patients with schizophrenia with
mission to look for markers for
two types characteristics one is
markers that distinguishes
patients with different types
schizophrenia technical workers
second recall is to find markers
that change with time when
treatment is applied to those
patients are collaborations with
radiology are absolutely crucial
to the success of our group
psychiatry like other medical
field is moving to precision
medicine we think that grouping
patients by these biomarkers
will really allow for a new era
of testing and developing
different interventions genetics
is a new component of the
inspires program we embarked on
a study year and a half ago to
look for mutations and their
trophy and James and a set of
schizophrenic subjects and we
actually found some very
interesting mutations in these
jeans suggest that they may be
involved at some level and
progression of schizophrenia and
most of these conditions the
jeans are telling only a small
amount of the story
the more we learn about the
jeans the more we see that its
other life course exposures that
also influenced mental health
things that people calm nature
and culture most conventionally
are of course depleting not only
intertwined but co-produced
reshape the environment which
Helton illness and the
individuality of people and
their experiences and the
vulnerabilities and resilience
PSA's of children of their
families of their communities
and inspires has been able to
think about what is shaping what
then becomes a kind of a health
thing that having inspires here
at NYU has meant for me and for
so many other trainees and young
psychiatrist has been an
environment that really foster's
are most creative thinking and
it's made an enormous difference
for my ability to think in a
creative way and
interdisciplinary way to think
outside of the received wisdom
about psychiatric problems
and the way that they develop
and to find new solutions to
draw from well outside of
psychiatry and unexpected ways
it's very exciting to sit around
the table to present were can't
hear feedback from very
different perspectives that
crosstalk that really
invigorates working at cross

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InSPIRES is a cross-disciplinary initiative that aims to illuminate the multiple pathways to mental illness and resilience across the generations and over an individual’s life course. A goal is to identify the indicators for person-specific treatments and cures, which are seriously lacking, particularly for the psychoses. The intersecting research components of InSPIRES consider genetic and epigenetic factors and exposures linked to mental illness. In other studies we are deciphering the overlapping pathways to metabolic and mental disorders. To link the relevant etiologies and the indicators of optimal treatment, InSPIRES considers the biomarkers that are closest to brain disruption using state of the art novel neuroimaging approaches, cognitive studies, psychophysiology and biobehavioral measures. The group also collaborates with a unique group in anthropology that is aiming to forge a common language between the life science and humanities. Finally, InSPIRES is an important and training platform for graduate and medical students, residents, postdoctoral fellows and NIH funded K awardees.